Sarah Silverman: "Nothing’s more attractive than an unending monologue about your shortcomings."
Carolyn Hax: "Sometimes surrendering to the awful is more useful than fighting it."
Graham Joyce: "why can’t our job here on earth be simply to inspire each other?"
Dan Harmon: "I believe in magic. I believe in mythology. I believe in shamanism. I believe that spells can be cast and I believe that random things coalesce and reveal themselves to be part of a plan we don’t control, you know."
Nora Ephron: "Never turn down a front-row seat for human folly."
McAlvie "The ultimate downfall of modern civilization won't be war; it'll be Twitter and Facebook."
Jenny Zhang: "A lot of writers swear by routine, but I swear by chaos. There’s enough fucking routine in my life. Every day I have to brush my teeth. Every day I have to smile at strangers. Every day I have to worry about money. Every day I want something I can’t have. Every day I find some way to go on! I know that writing every day for an hour would help me tremendously with writer’s block, but I also know that I need an element of wildness in my writing. I need to know that writing is something I do because it sets me free. It makes me feel golden with confidence. It gives me the gift of gab. I feel like a god. I feel like an entertainer. So write when you damn well please."
Joe Queenan: "If you have read 6,000 books in your lifetime, or even 600, it's probably because at some level you find "reality" a bit of a disappointment. People in the 19th century fell in love with "Ivanhoe" and "The Count of Monte Cristo" because they loathed the age they were living through. Women in our own era read "Pride and Prejudice" and "Jane Eyre" and even "The Bridges of Madison County"—a dimwit, hayseed reworking of "Madame Bovary"—because they imagine how much happier they would be if their husbands did not spend quite so much time with their drunken, illiterate golf buddies down at Myrtle Beach. A blind bigamist nobleman with a ruined castle and an insane, incinerated first wife beats those losers any day of the week. Blind, two-timing noblemen never wear belted shorts."
LogicalDash: "Nobody of any age should have to fend off sexual partners. That such defense is assumed as a part of the cost of adult courtship is suggestive of some more fundamental problem than age difference and its effect on consensuality."
Keith Richards: "I had to invent the job, you know," he said, earlier. "There wasn't a sign in the shop window, saying, "Wanted: Keith Richards."
Caitlin Moran: "As I started to reassess my writing style, I thought about what I liked doing--what gave me satisfaction--and realized the primary one was just... pointing at things. Pointing out things I liked, and showing them to other people--like a mum shouting, "Look! Moo-cows!" as a train rushes past a farm. I liked pointing at things, and I liked being reasonable and polite about stuff. Or silly. Silly was very, very good. No one ever got hurt by silly.
Best of all was being pointedly silly about serious things: politics, repression, bigotry. Too many commentators are quick to accuse their enemies of being evil. It's far, far more effective to point out that they're acting like idiots, instead. I was up for idiot-revealing.
"I am just going to be polite and silly, and point at cool things," I decided. "When I started writing, I would have killed to have one thing to write about. Now, I have three. Politeness and silliness, and pointing. That's enough."
Carolyn Hax: "Unless 15 years’ worth of mail has misled me, no one has ever found love through complaining about the lack of it, and no lonely person has ever felt better for hearing, “You just haven’t found the right person yet.”
David Simon: "Change is a motherfucker when you run from it."
Joe Queenan: "People who read an enormous number of books are basically dissatisfied with the way things are going on this planet. And I think, in a way, people read for the same reason that kids play video games ... they like that world better. It works better, it's more exciting, and it usually has a more satisfactory ending."
Dan Savage: "There isn't someone for everyone. Some of us do wind up alone, and that just fucking sucks and sometimes that stings, and you don't know if you're one of those people who's going to wind up alone until you die alone....So you kind of have to live in hope and build a life for yourself that's rewarding and fun, has friends and pleasure in it, whether you're alone or not."
the painkiller: "I will not be tagged, pinned, circled, liked, tweeted, retweeted or numbered."
Steve Jobs: "Of course it was impossible to connect the dots looking forward when I was in college. But it was very, very clear looking backwards ten years later.
Again, you can't connect the dots looking forward; you can only connect them looking backwards. So you have to trust that the dots will somehow connect in your future. You have to trust in something — your gut, destiny, life, karma, whatever. This approach has never let me down, and it has made all the difference in my life.”
Apple: "Here’s to the crazy ones. The misfits. The rebels. The troublemakers. The round pegs in the square holes. The ones who see things differently. They’re not fond of rules. And they have no respect for the status quo. You can quote them, disagree with them, glorify or vilify them. About the only thing you can’t do is ignore them. Because they change things. They push the human race forward. And while some may see them as the crazy ones, we see genius. Because the people who are crazy enough to think they can change the world, are the ones who do."
Miss Manners: "Please do not -- repeat, not -- make a hostile approach to knitters. Have you not noticed that they are armed with long, pointy sticks?"
Stephen Tobolowsky: "And of course, nothing is what I figured on in my life. That seems to be a recurring theme."
James Bulls: "When you find yourself walking a true path, you will know it because you will want to walk it no matter the burning Sun, freezing sleet, torrential rain, and treacherous ground. The risks become no less and the journey as always exhausts you, but your desire to brave the challenges never diminishes."
Amy Argetsinger: "Twitter is a disease, plain and simple. It makes people insane. A decade from now I expect the CDC and FDA will be issuing warnings."
Cary Tennis: "You don't have to "move on" either. Not until you're ready. People say, Oh, you should be grateful. They say, Oh, it's time for you to move on. I'm like, What are you, a cop with a nightstick? I'll move on when I'm done playing the blues on my harmonica, thank you very much."
Mark Morford: "It is 2011 and here is what we know: Reality is fluid, fact is malleable, cause and effect completely uncertain. We know what we don't know, but we also know the opposite."
Charlie Jane Anders: "Just remember, if you flinch from your destiny, you'll never achieve your true greatness — you didn't choose to be chosen, but being chosen means you have to choose."
Roger Ebert: "To put it bluntly, I believe the world is patriarchal because men are bigger and stronger than women, and can beat them up."
Myca: "Jesus is not the reason for the season, and there's no way I need to act like he is. Christmas is a stolen tradition. There's no reason we can't steal it back."
Lady Gaga: "I hate the holidays! I'm alone and miserable, you fucking dumb bit of toy!"
Dianna Agron: "I am trying to live my life with a sharpie marker approach. You can’t erase the strokes you’ve made, but each step is much bolder and more deliberate."
John Mayer: "It occurred to me that since the invocation of Twitter, nobody who has participated in it has created any lasting art. And yes! Yours truly is included in that roundup as well. Let me make sure that statement is as absolute and irrevocable as possible by buzzing your tower one more time: no artwork created by someone with a healthy grasp of social media thus far has proven to be anything other than disposable."
Vanessa, Something Positive: "I like 'em crazy. You hear insane rants, I hear a reminder that the sex is interesting. Oooh! Hear that? Tonight's gonna tingle."
Anonymous: “Your problem is that you want to be an artist. What you need to be is an artisan.”
Sugar: "Ask better questions, sweet pea. The fuck is your life. Answer it."
Wide Lawns: "Often very odd things happen to me. Usually they are not my fault and mostly beyond my control."
Anonymous reporter: “When weird shit happens around here, weird shit really happens around here.”
Anne Johnson: "Today some stranger sent me an email that said, "You are a nut case." Well, I must admit this never would have occurred to me. Everyone else is a nut case. I'm the sane one. I think."
Carl Mayer: "Whenever I start to feel like my life isn’t where I want it to be, “Cops” is there to put everything into perspective. Yeah, I haven’t made all the right moves over the last 34 years, but I’m not hiding from the police under a kiddie pool, either."
John Scalzi: "In retrospect, it’s a little weird to think that my entire future was falling into place as I obliviously tucked into the El Presidente chimichanga platter, but of course, that’s life for you — the most important days of your existence don’t always announce themselves in obvious ways."
Tart and Soul: "Indeed, love comes whether we have braced ourselves for it or not. But commitment offers a choice, tapping us on the shoulder to say, “sorry to bother you. Is this a good time?”
"NASA needed astronauts to go plant a flag on the moon. For obvious reasons, the astronauts ended up being the most reliable type of man America makes: white, straight, full-starch protestant, center-right, and spawned by the union of science and the military. Every last one of them was the heart of the heart of the tv dinner demographic. But then
they get shot into space, tossed from the gravity of this planet, across a quartermillion miles of nothing, to be snagged by the moon after three days. Eighteen guys did this and twelve descended further to find out that moon dust smells like gunsmoke. Every single one of them came back irrevocably changed. America had sent the squarest motherfuckers it could find to the moon and the moon sent back humans. Armstrong became a teacher, then a farmer. Alan Bean became a painter. Edgar Mitchell started believing in UFOs."
"But the press seemed more interested in the headline, “Astronaut Does ESP Experiment on Moon Flight.” Somehow word got out that it turned out to be without significance when in reality the results were completely in keeping with experiments conducted before and after in laboratories around the world. It appears that even great distances -- hundreds of thousands of miles -- do not alter this mysterious communication. When we compared my four sets of data -- two on days outbound, and two returning from the moon -- with the six data sets of individuals participating on Earth, we saw we’d achieved a “psi missing” result for the days I did the experiment and “chance” results for the other days. The psi missing statistics were such that there was only a 1-in-3,000 probability that our results were random!
After my space flight, I was contacted by some descendants of the original Roswell observers, including the person who delivered the child-sized coffins to the Air Force to contain the alien bodies. Another was one of the children of the deputy sheriff who was patrolling traffic around the site back then. There was also a military officer who was a friend of the families not involved in that particular operation, but who did share office space there. They all seemed credible with their stories that the bodies were alien."
"So I came back and started studying the mystical traditions, Uri Geller, and the inner religious experiences of humans. Because of my epiphany in space, I have come back and spent 30 years trying to explain what mind-brain is.
How did you meet Uri Geller?
The gentleman who was originally doing work with him, Dr. Andrija Puharich, called me and asked me if I was interested in meeting him. Geller has been investigated many times all over the world by scientists and magicians who are trying to debunk him. You have to work with these people on their terms. You find out what their shtick is, so to speak, and you set up a science protocol that works within the parameters that they are comfortable with. We did not set up a controlled experiment to do teleportation, for example. We didn't really know how to do that.
But you did ask him if he could teleport a camera you forgot on the moon?
That was really more of a joke, because I was annoyed with him. We were trying to get work done in the laboratory, and it wasn't working, and Geller said that he was good with teleportation. So I said "OK, teleport back the camera I left on the moon." He didn't get the camera back but he did get two lost tiepins of mine back. A piece of one of them showed up in Geller's mouth as he was eating ice cream, to the surprise of all of us. The other tiepin and the rest of the first one then showed up in the laboratory. One piece turned up right in front of Dr. Puthoff when he was with a group of people, and the other dropped to the floor between Dr. Puthoff and me when we were in the laboratory alone. "
"Ketamine, popularly known as the psychedelic club drug Special K, has been around since the early 1960s. It is a staple anesthetic in emergency rooms, regularly used for children when they come in with broken bones and dislocated shoulders. It’s an important tool in burn centers and veterinary medicine, as well as a notorious date-rape drug, known for its power to quickly numb and render someone immobile.
Since 2006, dozens of studies have reported that it can also reverse the kind of severe depression that traditional antidepressants often don’t touch.
Experts are calling it the most significant advance in mental health in more than half a century. They point to studies showing ketamine not only produces a rapid and robust antidepressant effect; it also puts a quick end to suicidal thinking.
Traditional antidepressants and mood stabilizers, by comparison, can take weeks or months to work. In 2010, a major study published in JAMA, the journal of the American Medical Association, reported that drugs in a leading class of antidepressants were no better than placebos for most depression.
A growing number of academic medical centers, including Yale University, the University of California at San Diego, the Mayo Clinic and the Cleveland Clinic, have begun offering ketamine treatments off-label for severe depression, as has Kaiser Permanente in Northern California.
This is the next big thing in psychiatry,” says L. Alison McInnes, a San Francisco psychiatrist who over the past year has enrolled 58 severely depressed patients in Kaiser’s San Francisco clinic. She says her long-term success rate of 60 percent for people with treatment-resistant depression who try the drug has persuaded Kaiser to expand treatment to two other clinics in the Bay Area. The excitement stems from the fact that it’s working for patients who have spent years cycling through antidepressants, mood stabilizers and various therapies.
“Psychiatry has run out of gas” in trying to help depressed patients for whom nothing has worked, she says. “There is a significant number of people who don’t respond to antidepressants, and we’ve had nothing to offer them other than cognitive behavior therapy, electroshock therapy and transcranial stimulation.”
So how does it go?
“And the response rate is unbelievable. This drug is 75 percent effective, which means that three-quarters of my patients do well. Nothing in medicine has those kind of numbers.”
So far, there is no evidence of addiction at the low dose in which infusions are delivered. Ketamine does, however, have one major limitation: Its relief is temporary. Clinical trials at NIMH have found that relapse usually occurs about a week after a single infusion."
Overall, you got 15/15 correct. You also answered mismatched pairs 0.32 seconds faster than matched pairs, which is below the average score. True, 0.32 seconds faster sounds imperceptible, but your score here does give you some clues about your ability to tune out distractions. It suggests that you’re more susceptible to interferences – that is, distractions or other irrelevant information.
All pairs: Average response time
Mismatched pairs: Average response time
I thought I was cool, but apparently not?
"But on the other hand, Carson’s work has shown that high-achieving, highly intelligent creative individuals are seven times more likely to have a faulty latent inhibition filter — they never really get used to distractions like the cacophony of nearby construction workers, “and every time they hear the noise, they pay attention to it,” Carson explained.
In the parlance of a programmer, this may be more of a feature than it is a bug. If your filter is more “porous,” as Carson phrases it, then you’re taking in bits of information from your environment that others may be missing. This, in turn, may allow you to remix and recombine that new incoming information with what you already know, leading to novel ideas or solutions. As psychologist Scott Barry Kaufman and science writer Carolyn Gregoire write in their fascinating new book, Wired to Create, a creative mind also often tends to be a rather disorganized one. “Reduced latent inhibition speaks directly to the concept of a ‘messy mind,’” they write, “as it reflects a mind that [is] tuning into greater amounts of information from its surroundings rather than automatically filtering and compartmentalizing.”
"Cancer is not linear—it is completely non-linear. It lives in the science of chaos. There’s no single point of control. You need to attack it in a non-linear fashion across time and space, monitoring it and truly dancing with it. I know this sounds philosophical and silly and esoteric but it’s not."
Lois McMaster Bujold: Gentleman Jole and the Red Queen Reviewed February 8. (****)
Annette Gordon-Reed: The Hemingses of Monticello Reviewed February 15. (***)
Marie Brennan: A Natural History of Dragons: A Memoir By Lady Trent Reviewed February 12. (****)
Meljean Brook: Riveted Reviewed February 11. (****)
Steven Brust: Sethra Lavode Reviewed February 10. (****)
Steven Brust: The Lord of Castle Black Reviewed February 9. (****)
Steven Brust: The Paths of the Dead Reviewed February 8. (***)
Augusten Burroughs: This Is How: Proven Aid in Overcoming Shyness, Molestation, Fatness, Spinsterhood, Grief, Disease, Lushery, Decrepitude & More. For Young and Old Alike. Reviewed January 27. (*****)
Gabrielle Oettingen: Rethinking Positive Thinking: Inside The New Science of Motivation Reviewed January 26. (****)
Seanan McGuire: Indexing: Reflections: all chapter reviews Reviewed January 14. (****)
Michael Signer: Becoming Madison: The Extraordinary Origins of the Least Likely Founding Father Reviewed January 26. (***)
Seanan McGuire: Indexing: Reflections: Episode 24: Never After Reviewed January 12. (****)
Wildbow: Worm: Gestation 1.6 Reviewed January 21. (****)
Wildbow: Worm: Gestation 1.5 Reviewed January 20. (***)
Wildbow: Worm: Gestation 1.4 Reviewed January 19. (**)
Wildbow: Worm: Gestation 1.3 Reviewed January 18. (***)
Wildbow: Worm: Gestation 1.2 Reviewed January 15. (***)
David McCullough: John Adams Reviewed January 14. (****)
Elle Kennedy: The Deal Reviewed January 13. (****)
Rachel Schurig: Escape In You Reviewed January 12. (****)
Rachel Schurig: Relent (Ransom Series Book 4) Reviewed January 11. (****)
Rachel Schurig: Redeem (Ransom Series Book 3) Reviewed January 8. (****)
Rachel Schurig: Release (Ransom Series Book 2) Reviewed January 7. (****)